Participants are mailed an explanatory primer letter designed to encourage research participation (highlights the importance of participation in research studies, the benefits to the individual an to the community among others).
Sending a recruitment primer letter may have little or no effect on recruitment.
An increase of 0% (95% confidence interval = -6% to 6%).
GRADE Low certainty.
We recommend that trialists send a pre-recruitment primer letter in the context of an intervention evaluation.
See Resource bundle below for details on how to write pre-recruitment primer letters.
Imagine a trial that needs to recruit 30 participants and initial recruitment is 30% of those approached. This means you’d need to approach 100 people to recruit 30 of them (see chart).
Now imagine using sending a pre-recruitment primer letter. The chart below shows the impact of an absolute increase of 0% (95% CI = -6% to 6%). Recruitment is still 30%, which means our best estimate is that 100 people would still need to be approached to recruit 30 of them.